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Sinusitis: why distinguishing between inflammatory forms (including non-allergic) and purulent infection is essential

Sinusitis is one of the most common conditions seen in ENT practice, yet it remains widely misunderstood. Too often, all forms of sinusitis are treated the same way, leading to ineffective therapies or even harm. In reality, sinusitis is not a single disease: there are profoundly different types that require equally different approaches. In this article, we clarify the fundamental distinction between inflammatory sinusitis (with and without an allergic component) and purulent infectious sinusitis, and introduce a new active substance – Cucurbitacins B-D-I-E – which represents an absolute novelty in the therapeutic landscape for purulent forms.